This gene encodes a member of a family of small proline-rich proteins clustered in the epidermal differentiation complex on chromosome 1q21. The encoded protein, along with other family members, is a component of the cornified cell envelope that forms beneath the plasma membrane in terminally differentiated stratified squamous epithelia. This envelope serves as a barrier against extracellular and environmental factors. The seven SPRR2 genes (A-G) appear to have been homogenized by gene conversion compared to others in the cluster that exhibit greater differences in protein structure. [provided by RefSeq, Feb 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPRR2E-20-RE | 20 (40 μL) | 200 μL |  |
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| SPRR2E-20-OR | 20 (40 μL) | 200 μL |  |
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| SPRR2E-20-GO | 20 (40 μL) | 200 μL |  |
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| SPRR2E-20-GR | 20 (40 μL) | 200 μL |  |
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| SPRR2E-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a family of small proline-rich proteins clustered in the epidermal differentiation complex on chromosome 1q21. The encoded protein, along with other family members, is a component of the cornified cell envelope that forms beneath the plasma membrane in terminally differentiated stratified squamous epithelia. This envelope serves as a barrier against extracellular and environmental factors. The seven SPRR2 genes (A-G) appear to have been homogenized by gene conversion compared to others in the cluster that exhibit greater differences in protein structure. [provided by RefSeq, Feb 2014]
Gene Symbol : SPRR2E
Gene Name : Small proline rich protein 2E
Chromosome : CHR 1: 153,094,527-153,093,134
Locus : 1q21.3
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