This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPRY4-20-RE | 20 (40 μL) | 200 μL |  |
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| SPRY4-20-OR | 20 (40 μL) | 200 μL |  |
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| SPRY4-20-GO | 20 (40 μL) | 200 μL |  |
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| SPRY4-20-GR | 20 (40 μL) | 200 μL |  |
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| SPRY4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Symbol : SPRY4
Gene Name : Sprouty RTK signaling antagonist 4
Chromosome : CHR 5: 142,325,054-142,310,426
Locus : 5q31.3
Alt. Genes : SGK2
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