This gene produces a non-coding RNA that is upregulated in several different tumors, including melanoma and breast and prostate cancer cells. This transcript may mediate cell growth, proliferation, and apoptosis. It regulates levels of lipin 2, and therefore may be involved in lipid biosynthesis. The primary transcript is cleaved to release a mature product that localizes to the cytoplasm (PMID:25344859). The full length structure of the primary and cleaved transcripts is unclear, and it is possible that the primary transcript is a splice variant of SPRY4 (sprouty RTK signaling antagonist 4). [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPRY4-IT1-20-RE | 20 (40 μL) | 200 μL |  |
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| SPRY4-IT1-20-OR | 20 (40 μL) | 200 μL |  |
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| SPRY4-IT1-20-GO | 20 (40 μL) | 200 μL |  |
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| SPRY4-IT1-20-GR | 20 (40 μL) | 200 μL |  |
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| SPRY4-IT1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene produces a non-coding RNA that is upregulated in several different tumors, including melanoma and breast and prostate cancer cells. This transcript may mediate cell growth, proliferation, and apoptosis. It regulates levels of lipin 2, and therefore may be involved in lipid biosynthesis. The primary transcript is cleaved to release a mature product that localizes to the cytoplasm (PMID:25344859). The full length structure of the primary and cleaved transcripts is unclear, and it is possible that the primary transcript is a splice variant of SPRY4 (sprouty RTK signaling antagonist 4). [provided by RefSeq, Feb 2016]
Gene Symbol : SPRY4-IT1
Gene Name : SPRY4 intronic transcript 1
Chromosome : CHR 5: 142,318,321-142,317,619
Locus : 5q31.3
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