Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPTSSB-20-RE | 20 (40 μL) | 200 μL |  |
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| SPTSSB-20-OR | 20 (40 μL) | 200 μL |  |
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| SPTSSB-20-GO | 20 (40 μL) | 200 μL |  |
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| SPTSSB-20-GR | 20 (40 μL) | 200 μL |  |
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| SPTSSB-20-AQ | 20 (40 μL) | 200 μL |  |
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Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]
Gene Symbol : SPTSSB
Gene Name : Serine palmitoyltransferase small subunit B
Chromosome : CHR 3: 161,373,122-161,344,783
Locus : 3q26.1
Alt. Genes : PDZK1IP1
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