The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SRD5A3-20-RE | 20 (40 μL) | 200 μL |  |
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| SRD5A3-20-OR | 20 (40 μL) | 200 μL |  |
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| SRD5A3-20-GO | 20 (40 μL) | 200 μL |  |
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| SRD5A3-20-GR | 20 (40 μL) | 200 μL |  |
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| SRD5A3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]
Gene Symbol : SRD5A3
Gene Name : Steroid 5 alpha-reductase 3
Chromosome : CHR 4: 553,461,13-553,730,99
Locus : 4q12
Alt. Genes : RBM12
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