This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SRGAP2-20-RE | 20 (40 μL) | 200 μL |  |
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| SRGAP2-20-OR | 20 (40 μL) | 200 μL |  |
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| SRGAP2-20-GO | 20 (40 μL) | 200 μL |  |
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| SRGAP2-20-GR | 20 (40 μL) | 200 μL |  |
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| SRGAP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]
Gene Symbol : SRGAP2
Gene Name : SLIT-ROBO Rho GTPase activating protein 2
Chromosome : CHR 1: 206,203,463-206,464,442
Locus : 1q32.1
Alt. Genes : FEM1B
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