This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2B locus. This duplicated locus lacks an internal exon, and thus this gene copy may not be functional. Expression of this locus appears to be much lower than the similar SLIT-ROBO Rho GTPase activating protein 2C (SRGAP2C) locus. The SRGAP2C locus has been shown to encode a protein that functions antagonistically to SLIT-ROBO Rho GTPase activating protein 2 in cortical neuron development. [provided by RefSeq, May 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SRGAP2D-20-RE | 20 (40 μL) | 200 μL |  |
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| SRGAP2D-20-OR | 20 (40 μL) | 200 μL |  |
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| SRGAP2D-20-GO | 20 (40 μL) | 200 μL |  |
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| SRGAP2D-20-GR | 20 (40 μL) | 200 μL |  |
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| SRGAP2D-20-AQ | 20 (40 μL) | 200 μL |  |
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This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2B locus. This duplicated locus lacks an internal exon, and thus this gene copy may not be functional. Expression of this locus appears to be much lower than the similar SLIT-ROBO Rho GTPase activating protein 2C (SRGAP2C) locus. The SRGAP2C locus has been shown to encode a protein that functions antagonistically to SLIT-ROBO Rho GTPase activating protein 2 in cortical neuron development. [provided by RefSeq, May 2014]
Gene Symbol : SRGAP2D
Gene Name : SLIT-ROBO Rho GTPase activating protein 2D (pseudogene)
Chromosome : CHR 1: 143,972,638-144,069,703
Locus : 1q21.1
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