This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SRGN-20-RE | 20 (40 μL) | 200 μL |  |
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| SRGN-20-OR | 20 (40 μL) | 200 μL |  |
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| SRGN-20-GO | 20 (40 μL) | 200 μL |  |
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| SRGN-20-GR | 20 (40 μL) | 200 μL |  |
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| SRGN-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Symbol : SRGN
Gene Name : Serglycin
Chromosome : CHR 10: 690,575,43-691,048,10
Locus : 10q22.1
Alt. Genes : G3BP1
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