The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ST6GALNAC4-20-RE | 20 (40 μL) | 200 μL |  |
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| ST6GALNAC4-20-OR | 20 (40 μL) | 200 μL |  |
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| ST6GALNAC4-20-GO | 20 (40 μL) | 200 μL |  |
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| ST6GALNAC4-20-GR | 20 (40 μL) | 200 μL |  |
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| ST6GALNAC4-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : ST6GALNAC4
Gene Name : ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
Chromosome : CHR 9: 127,917,051-127,907,885
Locus : 9q34.11
Alt. Genes : OPTN
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