This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STAM-20-RE | 20 (40 μL) | 200 μL |  |
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| STAM-20-OR | 20 (40 μL) | 200 μL |  |
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| STAM-20-GO | 20 (40 μL) | 200 μL |  |
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| STAM-20-GR | 20 (40 μL) | 200 μL |  |
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| STAM-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
Gene Symbol : STAM
Gene Name : Signal transducing adaptor molecule
Chromosome : CHR 10: 176,441,24-177,168,23
Locus : 10p12.33
Alt. Genes : FEM1B
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