This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STARD13-20-RE | 20 (40 μL) | 200 μL |  |
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| STARD13-20-OR | 20 (40 μL) | 200 μL |  |
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| STARD13-20-GO | 20 (40 μL) | 200 μL |  |
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| STARD13-20-GR | 20 (40 μL) | 200 μL |  |
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| STARD13-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Symbol : STARD13
Gene Name : StAR related lipid transfer domain containing 13
Chromosome : CHR 13: 336,768,34-331,031,34
Locus : 13q13.1-q13.2
Alt. Genes : OPTN
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