This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STK10-20-RE | 20 (40 μL) | 200 μL |  |
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| STK10-20-OR | 20 (40 μL) | 200 μL |  |
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| STK10-20-GO | 20 (40 μL) | 200 μL |  |
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| STK10-20-GR | 20 (40 μL) | 200 μL |  |
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| STK10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]
Gene Symbol : STK10
Gene Name : Serine/threonine kinase 10
Chromosome : CHR 5: 172,188,341-172,042,069
Locus : 5q35.1
Alt. Genes : RBM12
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