This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STK11-20-RE | 20 (40 μL) | 200 μL |  |
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| STK11-20-OR | 20 (40 μL) | 200 μL |  |
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| STK11-20-GO | 20 (40 μL) | 200 μL |  |
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| STK11-20-GR | 20 (40 μL) | 200 μL |  |
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| STK11-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : STK11
Gene Name : Serine/threonine kinase 11
Chromosome : CHR 19: 120,579,8-122,843,4
Locus : 19p13.3
Alt. Genes : OPTN
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