This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STK3-20-RE | 20 (40 μL) | 200 μL |  |
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| STK3-20-OR | 20 (40 μL) | 200 μL |  |
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| STK3-20-GO | 20 (40 μL) | 200 μL |  |
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| STK3-20-GR | 20 (40 μL) | 200 μL |  |
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| STK3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Symbol : STK3
Gene Name : Serine/threonine kinase 3
Chromosome : CHR 8: 989,443,28-984,296,76
Locus : 8q22.2
Alt. Genes : LINC01587
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