This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
STS-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
STS-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
STS-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
STS-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
STS-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016]
Gene Symbol : STS
Gene Name : Steroid sulfatase
Chromosome : CHR X: 714,725,1-735,464,2
Locus : Xp22.31
Alt. Genes : EBI3
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