This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SUCLG1-20-RE | 20 (40 μL) | 200 μL |  |
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| SUCLG1-20-OR | 20 (40 μL) | 200 μL |  |
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| SUCLG1-20-GO | 20 (40 μL) | 200 μL |  |
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| SUCLG1-20-GR | 20 (40 μL) | 200 μL |  |
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| SUCLG1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]
Gene Symbol : SUCLG1
Gene Name : Succinate-CoA ligase alpha subunit
Chromosome : CHR 2: 844,594,61-844,235,22
Locus : 2p11.2
Alt. Genes : LRPPRC
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