Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SULF2-20-RE | 20 (40 μL) | 200 μL |  |
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| SULF2-20-OR | 20 (40 μL) | 200 μL |  |
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| SULF2-20-GO | 20 (40 μL) | 200 μL |  |
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| SULF2-20-GR | 20 (40 μL) | 200 μL |  |
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| SULF2-20-AQ | 20 (40 μL) | 200 μL |  |
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Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
Gene Symbol : SULF2
Gene Name : Sulfatase 2
Chromosome : CHR 20: 477,866,28-476,545,83
Locus : 20q13.12
Alt. Genes : YAF2
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