This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SUMO1-20-RE | 20 (40 μL) | 200 μL |  |
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| SUMO1-20-OR | 20 (40 μL) | 200 μL |  |
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| SUMO1-20-GO | 20 (40 μL) | 200 μL |  |
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| SUMO1-20-GR | 20 (40 μL) | 200 μL |  |
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| SUMO1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : SUMO1
Gene Name : Small ubiquitin-like modifier 1
Chromosome : CHR 2: 202,238,598-202,206,179
Locus : 2q33.1
Alt. Genes : HIPK3
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