This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SUV39H1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
SUV39H1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
SUV39H1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
SUV39H1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
SUV39H1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Symbol : SUV39H1
Gene Name : Suppressor of variegation 3-9 homolog 1
Chromosome : CHR X: 486,955,53-487,090,15
Locus : Xp11.23
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