This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SYCE1-20-RE | 20 (40 μL) | 200 μL |  |
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| SYCE1-20-OR | 20 (40 μL) | 200 μL |  |
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| SYCE1-20-GO | 20 (40 μL) | 200 μL |  |
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| SYCE1-20-GR | 20 (40 μL) | 200 μL |  |
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| SYCE1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Gene Symbol : SYCE1
Gene Name : Synaptonemal complex central element protein 1
Chromosome : CHR 10: 133,568,290-133,553,899
Locus : 10q26.3
Alt. Genes : TRIM28
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