This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SYMPK-20-RE | 20 (40 μL) | 200 μL |  |
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| SYMPK-20-OR | 20 (40 μL) | 200 μL |  |
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| SYMPK-20-GO | 20 (40 μL) | 200 μL |  |
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| SYMPK-20-GR | 20 (40 μL) | 200 μL |  |
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| SYMPK-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]
Gene Symbol : SYMPK
Gene Name : Symplekin
Chromosome : CHR 19: 458,632,89-458,154,41
Locus : 19q13.32
Alt. Genes : LRPPRC
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