Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAF1C-20-RE | 20 (40 μL) | 200 μL |  |
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| TAF1C-20-OR | 20 (40 μL) | 200 μL |  |
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| TAF1C-20-GO | 20 (40 μL) | 200 μL |  |
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| TAF1C-20-GR | 20 (40 μL) | 200 μL |  |
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| TAF1C-20-AQ | 20 (40 μL) | 200 μL |  |
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Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]
Gene Symbol : TAF1C
Gene Name : TATA-box binding protein associated factor, RNA polymerase I subunit C
Chromosome : CHR 16: 841,870,69-841,778,46
Locus : 16q24.1
Alt. Genes : TRIM28
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