This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAX1BP1-20-RE | 20 (40 μL) | 200 μL |  |
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| TAX1BP1-20-OR | 20 (40 μL) | 200 μL |  |
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| TAX1BP1-20-GO | 20 (40 μL) | 200 μL |  |
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| TAX1BP1-20-GR | 20 (40 μL) | 200 μL |  |
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| TAX1BP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
Gene Symbol : TAX1BP1
Gene Name : Tax1 binding protein 1
Chromosome : CHR 7: 277,393,72-278,297,66
Locus : 7p15.2
Alt. Genes : OPTN
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