The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TBK1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBK1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBK1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBK1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| TBK1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
Gene Symbol : TBK1
Gene Name : TANK binding kinase 1
Chromosome : CHR 12: 644,520,59-645,021,18
Locus : 12q14.2
Alt. Genes : TRAP1
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.