Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TCAP-20-RE | 20 (40 μL) | 200 μL |  |
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| TCAP-20-OR | 20 (40 μL) | 200 μL |  |
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| TCAP-20-GO | 20 (40 μL) | 200 μL |  |
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| TCAP-20-GR | 20 (40 μL) | 200 μL |  |
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| TCAP-20-AQ | 20 (40 μL) | 200 μL |  |
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Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008]
Gene Symbol : TCAP
Gene Name : Titin-cap
Chromosome : CHR 17: 396,653,45-396,665,53
Locus : 17q12
Alt. Genes : CELA3A
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