This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TDO2-20-RE | 20 (40 μL) | 200 μL |  |
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| TDO2-20-OR | 20 (40 μL) | 200 μL |  |
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| TDO2-20-GO | 20 (40 μL) | 200 μL |  |
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| TDO2-20-GR | 20 (40 μL) | 200 μL |  |
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| TDO2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
Gene Symbol : TDO2
Gene Name : Tryptophan 2,3-dioxygenase
Chromosome : CHR 4: 155,903,692-155,920,405
Locus : 4q32.1
Alt. Genes : FEM1B
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