This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TDP2-20-RE | 20 (40 μL) | 200 μL |  |
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| TDP2-20-OR | 20 (40 μL) | 200 μL |  |
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| TDP2-20-GO | 20 (40 μL) | 200 μL |  |
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| TDP2-20-GR | 20 (40 μL) | 200 μL |  |
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| TDP2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008]
Gene Symbol : TDP2
Gene Name : Tyrosyl-DNA phosphodiesterase 2
Chromosome : CHR 6: 246,668,86-246,499,76
Locus : 6p22.3
Alt. Genes : OPTN
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