This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia. [provided by RefSeq, Apr 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TEX15-20-RE | 20 (40 μL) | 200 μL |  |
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| TEX15-20-OR | 20 (40 μL) | 200 μL |  |
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| TEX15-20-GO | 20 (40 μL) | 200 μL |  |
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| TEX15-20-GR | 20 (40 μL) | 200 μL |  |
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| TEX15-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia. [provided by RefSeq, Apr 2017]
Gene Symbol : TEX15
Gene Name : Testis expressed 15, meiosis and synapsis associated
Chromosome : CHR 8: 309,130,11-308,315,43
Locus : 8p12
Alt. Genes : ABI2
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