This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TFR2-20-RE | 20 (40 μL) | 200 μL |  |
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| TFR2-20-OR | 20 (40 μL) | 200 μL |  |
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| TFR2-20-GO | 20 (40 μL) | 200 μL |  |
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| TFR2-20-GR | 20 (40 μL) | 200 μL |  |
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| TFR2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Gene Symbol : TFR2
Gene Name : Transferrin receptor 2
Chromosome : CHR 7: 100,642,779-100,620,415
Locus : 7q22.1
Alt. Genes : EBI3
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