The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TGIF2-20-RE | 20 (40 μL) | 200 μL |  |
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| TGIF2-20-OR | 20 (40 μL) | 200 μL |  |
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| TGIF2-20-GO | 20 (40 μL) | 200 μL |  |
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| TGIF2-20-GR | 20 (40 μL) | 200 μL |  |
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| TGIF2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]
Gene Symbol : TGIF2
Gene Name : TGFB induced factor homeobox 2
Chromosome : CHR 20: 365,734,72-365,939,51
Locus : 20q11.23
Alt. Genes : MPZL2
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