The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| THBD-20-RE | 20 (40 μL) | 200 μL |  |
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| THBD-20-OR | 20 (40 μL) | 200 μL |  |
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| THBD-20-GO | 20 (40 μL) | 200 μL |  |
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| THBD-20-GR | 20 (40 μL) | 200 μL |  |
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| THBD-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
Gene Symbol : THBD
Gene Name : Thrombomodulin
Chromosome : CHR 20: 230,496,63-230,456,32
Locus : 20p11.21
Alt. Genes : HNRNPA3P1
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