The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| THG1L-20-RE | 20 (40 μL) | 200 μL |  |
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| THG1L-20-OR | 20 (40 μL) | 200 μL |  |
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| THG1L-20-GO | 20 (40 μL) | 200 μL |  |
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| THG1L-20-GR | 20 (40 μL) | 200 μL |  |
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| THG1L-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Symbol : THG1L
Gene Name : TRNA-histidine guanylyltransferase 1 like
Chromosome : CHR 5: 157,731,388-157,741,448
Locus : 5q33.3
Alt. Genes : PREB
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