This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TICAM1-20-RE | 20 (40 μL) | 200 μL |  |
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| TICAM1-20-OR | 20 (40 μL) | 200 μL |  |
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| TICAM1-20-GO | 20 (40 μL) | 200 μL |  |
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| TICAM1-20-GR | 20 (40 μL) | 200 μL |  |
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| TICAM1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012]
Gene Symbol : TICAM1
Gene Name : Toll like receptor adaptor molecule 1
Chromosome : CHR 19: 483,174,1-481,592,3
Locus : 19p13.3
Alt. Genes : CLEC3A
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