This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TIGIT-20-RE | 20 (40 μL) | 200 μL |  |
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| TIGIT-20-OR | 20 (40 μL) | 200 μL |  |
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| TIGIT-20-GO | 20 (40 μL) | 200 μL |  |
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| TIGIT-20-GR | 20 (40 μL) | 200 μL |  |
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| TIGIT-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
Gene Symbol : TIGIT
Gene Name : T-cell immunoreceptor with Ig and ITIM domains
Chromosome : CHR 3: 114,293,985-114,310,287
Locus : 3q13.31
Alt. Genes : ATP6AP2
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