This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TIMP3-20-RE | 20 (40 μL) | 200 μL |  |
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| TIMP3-20-OR | 20 (40 μL) | 200 μL |  |
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| TIMP3-20-GO | 20 (40 μL) | 200 μL |  |
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| TIMP3-20-GR | 20 (40 μL) | 200 μL |  |
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| TIMP3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]
Gene Symbol : TIMP3
Gene Name : TIMP metallopeptidase inhibitor 3
Chromosome : CHR 22: 328,008,15-328,630,40
Locus : 22q12.3
Alt. Genes : ZNF263
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