This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TLE3-20-RE | 20 (40 μL) | 200 μL |  |
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| TLE3-20-OR | 20 (40 μL) | 200 μL |  |
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| TLE3-20-GO | 20 (40 μL) | 200 μL |  |
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| TLE3-20-GR | 20 (40 μL) | 200 μL |  |
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| TLE3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
Gene Symbol : TLE3
Gene Name : Transducin like enhancer of split 3
Chromosome : CHR 15: 700,979,34-700,477,89
Locus : 15q23
Alt. Genes : G3BP1
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