The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TLK1-20-RE | 20 (40 μL) | 200 μL |  |
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| TLK1-20-OR | 20 (40 μL) | 200 μL |  |
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| TLK1-20-GO | 20 (40 μL) | 200 μL |  |
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| TLK1-20-GR | 20 (40 μL) | 200 μL |  |
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| TLK1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Symbol : TLK1
Gene Name : Tousled like kinase 1
Chromosome : CHR 2: 171,231,313-170,990,822
Locus : 2q31.1
Alt. Genes : HIPK3
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