This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMED10-20-RE | 20 (40 μL) | 200 μL |  |
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| TMED10-20-OR | 20 (40 μL) | 200 μL |  |
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| TMED10-20-GO | 20 (40 μL) | 200 μL |  |
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| TMED10-20-GR | 20 (40 μL) | 200 μL |  |
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| TMED10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
Gene Symbol : TMED10
Gene Name : Transmembrane p24 trafficking protein 10
Chromosome : CHR 14: 751,766,45-751,314,67
Locus : 14q24.3
Alt. Genes : LRPPRC
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