This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMEM123-20-RE | 20 (40 μL) | 200 μL |  |
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| TMEM123-20-OR | 20 (40 μL) | 200 μL |  |
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| TMEM123-20-GO | 20 (40 μL) | 200 μL |  |
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| TMEM123-20-GR | 20 (40 μL) | 200 μL |  |
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| TMEM123-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008]
Gene Symbol : TMEM123
Gene Name : Transmembrane protein 123
Chromosome : CHR 11: 102,453,043-102,396,324
Locus : 11q22.2
Alt. Genes : RBM7
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