Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMEM158-20-RE | 20 (40 μL) | 200 μL |  |
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| TMEM158-20-OR | 20 (40 μL) | 200 μL |  |
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| TMEM158-20-GO | 20 (40 μL) | 200 μL |  |
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| TMEM158-20-GR | 20 (40 μL) | 200 μL |  |
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| TMEM158-20-AQ | 20 (40 μL) | 200 μL |  |
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Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]
Gene Symbol : TMEM158
Gene Name : Transmembrane protein 158 (gene/pseudogene)
Chromosome : CHR 3: 452,263,21-452,244,63
Locus : 3p21.31
Alt. Genes : TRIM13
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