This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TMX2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
TMX2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
TMX2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
TMX2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
TMX2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017]
Gene Symbol : TMX2
Gene Name : Thioredoxin related transmembrane protein 2
Chromosome : CHR 11: 577,125,22-577,409,72
Locus : 11q12.1
Alt. Genes : HIPK3
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