This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMX4-20-RE | 20 (40 μL) | 200 μL |  |
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| TMX4-20-OR | 20 (40 μL) | 200 μL |  |
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| TMX4-20-GO | 20 (40 μL) | 200 μL |  |
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| TMX4-20-GR | 20 (40 μL) | 200 μL |  |
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| TMX4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017]
Gene Symbol : TMX4
Gene Name : Thioredoxin related transmembrane protein 4
Chromosome : CHR 20: 801,982,8-797,735,2
Locus : 20p12.3
Alt. Genes : AKAP9
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