This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNFRSF21-20-RE | 20 (40 μL) | 200 μL |  |
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| TNFRSF21-20-OR | 20 (40 μL) | 200 μL |  |
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| TNFRSF21-20-GO | 20 (40 μL) | 200 μL |  |
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| TNFRSF21-20-GR | 20 (40 μL) | 200 μL |  |
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| TNFRSF21-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013]
Gene Symbol : TNFRSF21
Gene Name : TNF receptor superfamily member 21
Chromosome : CHR 6: 473,099,75-472,315,26
Locus : 6p12.3
Alt. Genes : ZNF263
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