The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TNS1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
TNS1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
TNS1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
TNS1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
TNS1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Gene Symbol : TNS1
Gene Name : Tensin 1
Chromosome : CHR 2: 217,978,852-217,799,788
Locus : 2q35
Alt. Genes : ZNF263
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