This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus. [provided by RefSeq, Sep 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TOPORS-20-RE | 20 (40 μL) | 200 μL |  |
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| TOPORS-20-OR | 20 (40 μL) | 200 μL |  |
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| TOPORS-20-GO | 20 (40 μL) | 200 μL |  |
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| TOPORS-20-GR | 20 (40 μL) | 200 μL |  |
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| TOPORS-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus. [provided by RefSeq, Sep 2010]
Gene Symbol : TOPORS
Gene Name : TOP1 binding arginine/serine rich protein
Chromosome : CHR 9: 325,526,27-325,405,43
Locus : 9p21.1
Alt. Genes : YAF2
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