The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TOX3-20-RE | 20 (40 μL) | 200 μL |  |
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| TOX3-20-OR | 20 (40 μL) | 200 μL |  |
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| TOX3-20-GO | 20 (40 μL) | 200 μL |  |
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| TOX3-20-GR | 20 (40 μL) | 200 μL |  |
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| TOX3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]
Gene Symbol : TOX3
Gene Name : TOX high mobility group box family member 3
Chromosome : CHR 16: 525,478,01-524,364,14
Locus : 16q12.1
Alt. Genes : PREB
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