This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TPR-20-RE | 20 (40 μL) | 200 μL |  |
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| TPR-20-OR | 20 (40 μL) | 200 μL |  |
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| TPR-20-GO | 20 (40 μL) | 200 μL |  |
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| TPR-20-GR | 20 (40 μL) | 200 μL |  |
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| TPR-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008]
Gene Symbol : TPR
Gene Name : Translocated promoter region, nuclear basket protein
Chromosome : CHR 1: 186,375,324-186,311,651
Locus : 1q31.1
Alt. Genes : HIPK3
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