The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRADD-20-RE | 20 (40 μL) | 200 μL |  |
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| TRADD-20-OR | 20 (40 μL) | 200 μL |  |
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| TRADD-20-GO | 20 (40 μL) | 200 μL |  |
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| TRADD-20-GR | 20 (40 μL) | 200 μL |  |
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| TRADD-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
Gene Symbol : TRADD
Gene Name : TNFRSF1A associated via death domain
Chromosome : CHR 16: 671,599,08-671,541,84
Locus : 16q22.1
Alt. Genes : FEM1B
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