This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TREM2-20-RE | 20 (40 μL) | 200 μL |  |
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| TREM2-20-OR | 20 (40 μL) | 200 μL |  |
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| TREM2-20-GO | 20 (40 μL) | 200 μL |  |
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| TREM2-20-GR | 20 (40 μL) | 200 μL |  |
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| TREM2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
Gene Symbol : TREM2
Gene Name : Triggering receptor expressed on myeloid cells 2
Chromosome : CHR 6: 411,631,99-411,585,05
Locus : 6p21.1
Alt. Genes : LPAR6
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