The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRIB3-20-RE | 20 (40 μL) | 200 μL |  |
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| TRIB3-20-OR | 20 (40 μL) | 200 μL |  |
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| TRIB3-20-GO | 20 (40 μL) | 200 μL |  |
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| TRIB3-20-GR | 20 (40 μL) | 200 μL |  |
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| TRIB3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Symbol : TRIB3
Gene Name : Tribbles pseudokinase 3
Chromosome : CHR 20: 380,628-397,558
Locus : 20p13
Alt. Genes : CEBPZ
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